Introduction
We know that insulin acts as a key to let glucose into our cells. But what happens when the lock becomes rusty and the key doesn’t work anymore? This condition is called insulin resistance, and it is a primary driver of Type 2 diabetes.
The Breakdown of a System
In insulin resistance, your muscle, fat, and liver cells don’t respond well to insulin and can’t easily take up glucose from your blood. As a result, your blood sugar levels remain high.
- Sensing this high sugar, your pancreas works overtime, pumping out even more insulin to try to force glucose into the cells.
- For a while, this hyper-production of insulin can keep blood sugar levels within a normal range. This is often called “prediabetes.”
- Over time, however, the insulin-producing cells in the pancreas get exhausted and can’t keep up. Blood sugar levels then rise to diabetic levels.
What Causes Insulin Resistance?
Several factors contribute, including:
- Excess Body Fat: Particularly visceral fat around the abdomen, is highly active in releasing inflammatory substances that interfere with insulin’s action.
- Lack of Physical Activity: Muscles that are inactive are less sensitive to insulin.
- Genetics and Family History.
Reversing the Trend
The good news is that insulin resistance can often be improved and even reversed with lifestyle changes. Weight loss, especially, and regular exercise are the most powerful ways to help your cells become sensitive to insulin again, making the “key” work smoothly in the “lock” once more.